Zinc Ion

Zinc Ion

SCHEMBL9501068

S=C([S-])OCCOC(=S)[S-].[Zn+2]

nearest known ligand 0.55

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 19/20 0.55
CA2 P00918 19/20 0.55
CA12 O43570 17/20 0.55
CA9 Q16790 17/20 0.55
CA4 P22748 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Zinc Ion SCHEMBL15157993 0.82 CA12 (0.65) CA1CA2CA12CA9ALDH1A1
Potassium Ion SCHEMBL4848549 0.80
SCHEMBL9778631 0.80 CA12 (0.50) CA1CA2CA12CA9ALDH1A1
Zinc Ion SCHEMBL180551 0.78 CA12 (0.82) CA1CA2CA12CA9ALDH1A1
SCHEMBL9308111 0.76 CA12 (0.56) CA1CA2CA12CA9ALDH1A1
SCHEMBL9778605 0.76 CA12 (0.56) CA1CA2CA12CA9CA4
SCHEMBL9806594 0.76 CA12 (0.56) CA1CA2CA12CA9ALDH1A1
Potassium Ion SCHEMBL9306627 0.76 CA12 (0.61) CA1CA2CA12CA9ALDH1A1
Zinc Ion SCHEMBL15463383 0.76 CA12 (0.95) CA1CA2CA12CA9
SCHEMBL9307201 0.76 CA12 (0.56) CA1CA2CA12CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5211959-A Clathrates of urea JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1993-05-18 US disclosed
US-4434165-A Fungicidal compositions HOFFMANN-LA ROCHE INC. (US) 1984-02-28 US disclosed