Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FABP3 | P05413 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21875870 | 0.84 | DPP4 (0.50) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL1671686 | 0.82 | DPP4 (0.48) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL1673165 | 0.81 | DPP4 (0.47) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL117071 | 0.78 | DPP4 (0.62) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL29365114 | 0.78 | DPP4 (0.62) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| 2,3,6-Trichlorobenzoic Acid SCHEMBL10490012 | 0.76 | DPP4 (0.60) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL14167400 | 0.75 | BID (0.51) | DPP4KDM4EHSD17B10MCL1 | |
| SCHEMBL486824 | 0.75 | DPP4 (0.71) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL16702731 | 0.73 | DPP4 (0.68) | DPP4ALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL28737172 | 0.73 | DPP4 (0.68) | DPP4ALDH1A1KDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250696-A | Treatment of degenerative diseases | STERLING WINTHROP INC. (US) | 1993-10-05 | — | — | US | disclosed |