Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.61 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499675 | 1.00 | HTT (0.66) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL8962570 | 1.00 | HTT (0.66) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL9499422 | 1.00 | HTT (0.66) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL9220708 | 1.00 | HTT (0.66) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL2944311 | 1.00 | HTT (0.66) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL9499305 | 1.00 | HTT (0.66) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL9223916 | 0.98 | HTT (0.63) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL9499699 | 0.95 | HTT (0.59) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL10428236 | 0.89 | HTT (0.54) | HTTPOLBAPEX1TDP1TP53 | |
| SCHEMBL10428147 | 0.89 | HTT (0.54) | HTTPOLBAPEX1TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322708-B1 | POLYMERS WITH AMIDE GROUPS IN THE SIDE CHAINS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-04-28 | — | — | EP | disclosed |
| US-4925589-A | ADDITION ACRYLIC TYPE POLYMER | HOFFMANN-LA ROCHE INC. (US) | 1990-05-15 | — | — | US | disclosed |
| EP-0322708-A2 | Polymers with amide groups in the side chains | F. HOFFMANN-LA ROCHE AG (CH) | 1989-07-05 | — | — | EP | disclosed |