SCHEMBL9501402

SCHEMBL9501402

C=C(C)C(=O)OC(C)CO.C=CC(=O)OCCCCCCCO

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.43
TP53 P04637 2/20 0.36
HIF1A Q16665 2/20 0.36
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
APP P05067 2/20 0.32
ACHE P22303 6/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11109289 0.93 TSHR (0.43) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL11242606 0.84 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL30738367 0.83 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL8067773 0.83 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL1548476 0.83 TSHR (0.51) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL21819999 0.82 TSHR (0.46) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL3274720 0.82 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5835513 0.82 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL30673376 0.82 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7514830 0.81 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0225808-B1 PROCESS FOR PREPARING IMPROVED HIGH SOLIDS ACRYLIC-BASED COATINGS EXXON CHEMICAL PATENTS INC. (US) 1993-04-28 EP disclosed
EP-0521453-A1 Polymeric vehicle for coatings NORTH DAKOTA STATE UNIVERSITY (US) 1993-01-07 EP disclosed
US-5034154-A Solvents for hydroxy substituted alkyl acrylates EXXON CHEMICAL PATENTS INC. (US) 1991-07-23 US disclosed
EP-0148581-B1 HIGH SOLID COATINGS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1989-03-08 EP disclosed
US-4758642-A Process for preparing improved high solids acrylic-based coatings EXXON CHEMICAL PATENTS INC. (US) 1988-07-19 US disclosed
US-4739006-A BLEND CONTAINING ACRYLIC ESTERS AND HYDROXY SUBSTITUTED ACRYLIC ESTERS EXXON RESEARCH & ENGINEERING CO. (US) 1988-04-19 US disclosed
EP-0225808-A2 Process for preparing improved high solids acrylic-based coatings EXXON CHEMICAL PATENTS INC. (US) 1987-06-16 EP disclosed
US-4638031-A ELECTROSTATIC SPRAYING, POLYMERIZING HYDROXYALKYL AND ALKYL (METH) ACRYLATES, ESTER SOLVENT, FREE RADICAL CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1987-01-20 US disclosed
US-4593080-A Containing hydroxy-substituted alkyl (meth)acrylate EXXON RESEARCH & ENGINEERING CO. (US) 1986-06-03 US disclosed
US-4532294-A Contacting mixture of hydroxyalkyl acrylate, other acrylates in presence of free radical initiator, liquid ester solvent EXXON RESEARCH & ENGINEERING CO. (US) 1985-07-30 US disclosed
EP-0148581-A1 High solid coatings EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-07-17 EP disclosed
US-4501868-A METHYLISOBUTYL KETONE AND AN ALKYL-SUBSTITUTED BENZENE EXXON RESEARCH & ENGINEERING CO. (US) 1985-02-26 US disclosed
US-4276392-A FAST-CURING AUTOMOBILE TOPCOATS FORD MOTOR COMPANY (US) 1981-06-30 US disclosed
EP-0029683-A1 Coating composition FORD MOTOR COMPANY LIMITED (GB) 1981-06-03 EP disclosed