SCHEMBL9501425

SCHEMBL9501425

COC1CCC2CC(OC(=O)c3cc(Sc4ccccc4)c4c(c3N)C(=O)c3ccccc3C4=O)CCC2C1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.48
MAPT P10636 4/20 0.37
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
MAPK1 P28482 3/20 0.37
KDM4E B2RXH2 3/20 0.37
THRB P10828 2/20 0.37
USP2 O75604 1/20 0.37
PKM P14618 1/20 0.37
MCL1 Q07820 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
GRK6 P43250 1/20 0.35
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
SCN1A P35498 1/20 0.32
SCN2A Q99250 1/20 0.32
SCN3A Q9NY46 1/20 0.32
HTR3E A5X5Y0 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9501429 1.00 ADORA2A (0.48) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL9503036 0.94 ADORA2A (0.41) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL9501619 0.90 MAPT (0.37) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL9501615 0.90 MAPT (0.37) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL9501347 0.87 MAPT (0.35) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL9501351 0.87 MAPT (0.35) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL10584877 0.87 MAPT (0.38) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL9503088 0.86 ADORA2A (0.41) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL9501597 0.86 ADORA2A (0.41) ADORA2AMAPTMEN1KMT2AMAPK1
SCHEMBL9501661 0.86 MAPT (0.50) ADORA2AMAPTMEN1KMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0307866-B1 DICHROIC COLORING AGENTS FOR LIQUID CRYSTAL DISPLAYS MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP disclosed
US-4883611-A ANTHRAQUINONE COMPOUND CONTAINING DECAHYDRONAPHTHYL GROUP MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-11-28 US disclosed