Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26710742 | 1.00 | CCR1 (0.60) | CCR1SMN1; SMN2HPGDLMNAPKM | |
| SCHEMBL27748727 | 0.93 | CCR1 (0.68) | CCR1SMN1; SMN2NPC1TDP1DPP4 | |
| SCHEMBL425573 | 0.93 | CCR1 (0.68) | CCR1SMN1; SMN2NPC1TDP1DPP4 | |
| SCHEMBL26616529 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2HPGDLMNAPKMNPC1 | |
| SCHEMBL10749238 | 0.83 | SMN1; SMN2 (0.50) | CCR1SMN1; SMN2HPGDLMNAPKM | |
| SCHEMBL18631610 | 0.82 | DPP4 (0.55) | CCR1SMN1; SMN2NPC1TDP1DPP4 | |
| SCHEMBL18631609 | 0.82 | DPP4 (0.55) | CCR1SMN1; SMN2NPC1TDP1DPP4 | |
| SCHEMBL10291968 | 0.82 | CCR1 (0.89) | CCR1 | |
| SCHEMBL26616556 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDLMNAPKMHDAC3 | |
| SCHEMBL9503736 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2HPGDLMNAPKMHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232849-B1 | PYRROLIDINEAMIDE DERIVATIVE OF ACYLAMINO ACID, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5198458-A | Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same | SUNTORY LIMITED (JP) | 1993-03-30 | — | — | US | disclosed |
| US-4826870-A | CURING AMNESIA | SUNTORY LIMITED (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0232849-A2 | Pyrrolidineamide derivative of acylamino acid, pharmaceutical composition and use | SUNTORY LIMITED (JP) | 1987-08-19 | — | — | EP | disclosed |