SCHEMBL9501919

SCHEMBL9501919

CCCC/C(=N/O)NCc1ccc(-c2ccccc2C(=O)O)cc1

nearest known ligand 0.74

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R2 Q9NPC1 19/20 0.74
AGTR1 P30556 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9501923 1.00 LTB4R2 (0.74) LTB4R2AGTR1
SCHEMBL9597687 0.87 LTB4R2 (0.69) LTB4R2AGTR1
SCHEMBL9597692 0.87 LTB4R2 (0.69) LTB4R2AGTR1
SCHEMBL9498320 0.81 LTB4R2 (0.60) LTB4R2AGTR1
SCHEMBL9498314 0.81 LTB4R2 (0.60) LTB4R2AGTR1
SCHEMBL17727610 0.77 LTB4R2 (0.67) LTB4R2AGTR1
SCHEMBL3906504 0.76 BRS3 (0.70) LTB4R2AGTR1
SCHEMBL4192326 0.73 LTB4R2 (0.65) LTB4R2
Hexane SCHEMBL9090054 0.73 LTB4R2 (0.64) LTB4R2AGTR1
SCHEMBL10341051 0.73 LTB4R2 (0.65) LTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225408-A Biphenyl oxadiazinone angiotensin II inhibitors E. R. SQUIBB & SONS, INC. (US) 1993-07-06 US disclosed