Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14882745 | 0.84 | DPP4 (0.45) | MAPK1CYP3A4DPP4TSHRHPGD | |
| SCHEMBL4509639 | 0.83 | DPP4 (0.43) | MAPK1CYP3A4DPP4NOTUMTSHR | |
| SCHEMBL481034 | 0.83 | MAPT (0.44) | MAPK1CYP3A4HPGDMAPTALDH1A1 | |
| SCHEMBL403103 | 0.82 | CYP3A4 (0.42) | MAPK1CYP3A4NOTUMTSHRMAPT | |
| SCHEMBL30610932 | 0.82 | CYP3A4 (0.42) | MAPK1CYP3A4NOTUMTSHRMAPT | |
| SCHEMBL21822958 | 0.81 | MAPT (0.38) | MAPK1CYP3A4HPGDMAPTALDH1A1 | |
| SCHEMBL18542465 | 0.81 | TSHR (0.45) | DPP4TSHRHPGDMAPTALDH1A1 | |
| SCHEMBL30084375 | 0.80 | TSHR (0.54) | DPP4TSHRHPGDMAPTALDH1A1 | |
| SCHEMBL73043 | 0.80 | TSHR (0.54) | DPP4TSHRHPGDMAPTALDH1A1 | |
| SCHEMBL1901357 | 0.79 | MAOB (0.42) | MAPK1CYP3A4HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511233-B | Thiazolo [2,3-b ] oxazolone compound and preparation method and application thereof | 成都大学 | 2022-01-25 | — | — | CN | disclosed |
| EP-0305952-B1 | SUBSTITUTED 2-PHENYL-4-QUINOLINE-CARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1993-06-02 | — | — | EP | disclosed |
| US-4847381-A | ANTIARTHRITIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0305952-A1 | Substituted 2-phenyl-4-quinoline-carboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1989-03-08 | — | — | EP | disclosed |