⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9100994 | 1.00 | — | — | |
| SCHEMBL825743 | 1.00 | — | — | |
| SCHEMBL1959933 | 1.00 | — | — | |
| SCHEMBL4189582 | 1.00 | — | — | |
| SCHEMBL13947343 | 1.00 | — | — | |
| SCHEMBL10508488 | 1.00 | — | — | |
| SCHEMBL2335589 | 1.00 | — | — | |
| L-Fucose SCHEMBL3462756 | 0.91 | — | — | |
| L-Fucose SCHEMBL25051 | 0.91 | — | — | |
| L-Fucose SCHEMBL1746724 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385336-B1 | PROCESSES FOR THE PREPARATION OF PTERIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-06-02 | — | — | EP | claimed |
| US-5043446-A | Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-27 | — | — | US | claimed |
| EP-0385336-A2 | Processes for the preparation of pterin derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-09-05 | — | — | EP | claimed |
| JP-2225484-A | — | — | None | — | — | JP | disclosed |
| CN-113845441-B | Preparation method of tetrahydrobiopterin key intermediate | 北京阳光诺和药物研究股份有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-113845441-A | Preparation method of key intermediate of tetrahydrobiopterin | 北京阳光诺和药物研究股份有限公司 | 2021-12-28 | — | — | CN | disclosed |
| WO-2016189542-A1 | NOVEL PROCESS FOR THE PREPARATION OF SAPROPTERIN DIHYDROCHLORIDE AND ITS KEY INTERMEDIATE, L-BIOPTERIN | NATCO PHARMA LTD (IN) | 2016-12-01 | — | — | WO | disclosed |
| WO-2016101211-A1 | PREPARATION METHOD FOR SAPROPTERIN HYDROCHLORIDE | 北京卡威生物医药科技有限公司 | 2016-06-30 | — | — | WO | disclosed |
| EP-0385336-B1 | PROCESSES FOR THE PREPARATION OF PTERIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-5043446-A | Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| US-5043446-A | Subjecting ribose to acetalization, Grignard, oxidative cleavage, hydrazoning, condensing with pyridine to 1-biopterin | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0385336-A3 | PROCESSES FOR THE PREPARATION OF PTERIN DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1991-04-17 | — | — | EP | disclosed |
| JP-H02225484-A | PRODUCTION OF PTERIN DERIVATIVE | NISSHIN FLOUR MILLING CO LTD | 1990-09-07 | — | — | JP | disclosed |
| EP-0385336-A2 | Processes for the preparation of pterin derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |
| EP-0385336-A2 | Processes for the preparation of pterin derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-09-05 | — | — | EP | disclosed |