Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | RARA | P10276 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 7/20 | 0.46 |
| ▸ | THRB | P10828 | 7/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500809 | 1.00 | RARB (0.56) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9500362 | 0.97 | RARB (0.58) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9502017 | 0.97 | RARB (0.58) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9500047 | 0.97 | RARB (0.58) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9498977 | 0.97 | RARB (0.58) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9498765 | 0.96 | RARB (0.57) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9500452 | 0.96 | RARB (0.57) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9499152 | 0.95 | RARB (0.56) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9498357 | 0.94 | RARB (0.55) | RARBMEN1KMT2ARARAALDH1A1 | |
| SCHEMBL9502047 | 0.93 | RARB (0.53) | RARBMEN1KMT2ARARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |