Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.55 |
| ▸ | RARB | P10826 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.50 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500186 | 0.99 | TSHR (0.58) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL9500856 | 0.95 | RARB (0.61) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL91878 | 0.95 | RARB (0.61) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL17577041 | 0.94 | RARB (0.54) | TSHRTP53PLA2G4BRARBMAPT | |
| SCHEMBL9500251 | 0.92 | TSHR (0.58) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL9489466 | 0.89 | TSHR (0.52) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL9502153 | 0.89 | RARB (0.61) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL9488761 | 0.88 | TSHR (0.54) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL9488466 | 0.88 | TSHR (0.54) | TSHRTP53PLA2G4BRARBLMNA | |
| SCHEMBL9489062 | 0.88 | TSHR (0.54) | TSHRTP53PLA2G4BRARBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |