Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 4/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10574605 | 0.84 | PDE5A (0.58) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL10483928 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL9243916 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL8416991 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL9645798 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL9636121 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL9484734 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL8992296 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL8992277 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 | |
| SCHEMBL9647486 | 0.84 | CYP1A2 (0.48) | CYP1A2CYP2C9CYP2C19CYP19A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260077-B1 | PHENYL PYRIMIDINE COMPOUND AND LIQUID CRYSTALLINE COMPOSITION | AJINOMOTO CO., INC. (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4892676-A | FERROELECTRIC, HIGH SPEED RESPONSE | AJINOMOTO CO., INC. (JP) | 1990-01-09 | — | — | US | disclosed |
| EP-0260077-A1 | Phenyl pyrimidine compound and liquid crystalline composition | AJINOMOTO CO., INC. (JP) | 1988-03-16 | — | — | EP | disclosed |