SCHEMBL9502326

SCHEMBL9502326

CCOC1CCC2C[C@H](OC(=O)c3cc(Sc4ccc(Cl)cc4)c4c(c3N)C(=O)c3ccccc3C4=O)CC[C@@H]2C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.39
KDM4E B2RXH2 5/20 0.34
NPSR1 Q6W5P4 4/20 0.34
ALDH1A1 P00352 4/20 0.34
HPGD P15428 4/20 0.34
MAPT P10636 3/20 0.34
LMNA P02545 3/20 0.34
TNF P01375 1/20 0.34
HSP90AA1 P07900 1/20 0.34
ALOX12 P18054 1/20 0.34
CCR6 P51684 1/20 0.34
RUNX1 Q01196 1/20 0.34
CBFB Q13951 1/20 0.34
HKDC1 Q2TB90 1/20 0.34
NOD2 Q9HC29 1/20 0.34
GPR35 Q9HC97 1/20 0.34
NOD1 Q9Y239 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9502321 1.00 ADORA2A (0.39) ADORA2AKDM4ENPSR1ALDH1A1HPGD
SCHEMBL9503006 0.92 ADORA2A (0.38) ADORA2AKDM4ENPSR1ALDH1A1HPGD
SCHEMBL9503001 0.92 ADORA2A (0.38) ADORA2AKDM4ENPSR1ALDH1A1HPGD
SCHEMBL9501713 0.91 ADORA2A (0.39) ADORA2AKDM4ENPSR1ALDH1A1MAPT
SCHEMBL9501720 0.91 ADORA2A (0.39) ADORA2AKDM4ENPSR1ALDH1A1MAPT
SCHEMBL9504296 0.91 ADORA2A (0.41) ADORA2AKDM4ENPSR1ALDH1A1HPGD
SCHEMBL9504289 0.91 ADORA2A (0.41) ADORA2AKDM4ENPSR1ALDH1A1HPGD
SCHEMBL9505322 0.89 ADORA2A (0.40) ADORA2AKDM4ENPSR1ALDH1A1HPGD
SCHEMBL9505318 0.89 ADORA2A (0.40) ADORA2AKDM4ENPSR1ALDH1A1HPGD
SCHEMBL10580658 0.85 ADORA2A (0.39) ADORA2AKDM4ENPSR1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0307866-B1 DICHROIC COLORING AGENTS FOR LIQUID CRYSTAL DISPLAYS MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-05-12 EP disclosed
US-4883611-A ANTHRAQUINONE COMPOUND CONTAINING DECAHYDRONAPHTHYL GROUP MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-11-28 US disclosed