Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844757 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL11040165 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL9561986 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL11043016 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL11040168 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL9561988 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL10844754 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL11039249 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL9502493 | 1.00 | TLR4 (0.39) | TLR4NAAACYP2C9POLBHPGD | |
| SCHEMBL11404412 | 0.95 | CYP19A1 (0.39) | TLR4NAAACYP2C9POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5188758-A | Electrooptical display element using a supertwist liquid crystal having specified elastic constants | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1993-02-23 | — | — | US | disclosed |
| US-4871470-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |
| US-4799774-A | Electrooptical display element using a supertwist liquid crystal having specified elastic constants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-01-24 | — | — | US | disclosed |