Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.74 |
| ▸ | RARB | P10826 | 6/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.63 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374036 | 1.00 | PTPN11 (0.74) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL9502536 | 1.00 | PTPN11 (0.74) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL9689040 | 0.94 | PTPN11 (0.69) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8374033 | 0.94 | RARB (0.69) | PTPN11RARBTP53TSHRPLA2G4B | |
| Terephthalic Acid SCHEMBL9455932 | 0.87 | RARB (0.70) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL5355722 | 0.86 | PTPN11 (0.79) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL8376751 | 0.86 | PTPN11 (0.79) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL9182254 | 0.86 | PTPN11 (0.79) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL7169585 | 0.85 | PTPN11 (0.77) | PTPN11RARBTP53TSHRPLA2G4B | |
| SCHEMBL27245974 | 0.85 | PTPN11 (1.00) | PTPN11RARBTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110299-B2 | SMECTIC LIQUID CRYSTAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS | HITACHI, LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0110299-B1 | SMECTIC LIQUID CRYSTAL COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS | HITACHI, LTD. (JP) | 1988-06-29 | — | — | EP | disclosed |
| US-4576732-A | OPTICAL DISPLAYS | HITACHI, LTD. (JP) | 1986-03-18 | — | — | US | disclosed |
| EP-0110299-A2 | Smectic liquid crystal compounds and liquid crystal compositions | HITACHI, LTD. (JP) | 1984-06-13 | — | — | EP | disclosed |