Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | PTGES | O14684 | 1/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9501964 | 0.99 | CYP19A1 (0.73) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| SCHEMBL9502671 | 0.98 | CYP19A1 (0.72) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| SCHEMBL9502689 | 0.98 | CYP19A1 (0.72) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| SCHEMBL9502643 | 0.98 | CYP19A1 (0.73) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| SCHEMBL9502681 | 0.89 | CYP19A1 (0.56) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| SCHEMBL9501585 | 0.88 | CYP19A1 (0.59) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| Ns-398 SCHEMBL9505672 | 0.85 | CYP19A1 (0.98) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| SCHEMBL9504767 | 0.84 | CYP19A1 (1.00) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| Ns-398 SCHEMBL214213 | 0.84 | CYP19A1 (1.00) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 | |
| Ns-398 SCHEMBL29368077 | 0.84 | CYP19A1 (1.00) | CYP19A1PTGS1PTGS2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317332-B1 | SULFONANILIDE COMPOUNDS | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-4885367-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS; SIDE EFFECT REDUCTION | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1989-12-05 | — | — | US | disclosed |
| EP-0317332-A2 | Sulfonanilide compounds | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1989-05-24 | — | — | EP | disclosed |