Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941556 | 0.91 | MAPK1 (0.72) | MAPK1PRSS1TSHRCYP1A2CYP3A4 | |
| SCHEMBL12970778 | 0.88 | MAPK1 (0.72) | MAPK1PRSS1TSHRCYP1A2CYP3A4 | |
| SCHEMBL8137461 | 0.86 | TSHR (0.71) | MAPK1PRSS1TSHRCA12CA1 | |
| SCHEMBL8068426 | 0.85 | MAPK1 (0.68) | MAPK1PRSS1TSHRCYP1A2CYP3A4 | |
| SCHEMBL1545264 | 0.85 | MAPK1 (0.68) | MAPK1PRSS1TSHRCYP1A2CYP3A4 | |
| SCHEMBL29415167 | 0.85 | MAPK1 (0.77) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL335681 | 0.85 | MAPK1 (0.77) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6944861 | 0.84 | MAPK1 (1.00) | MAPK1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23630666 | 0.84 | MAPK1 (0.71) | MAPK1PRSS1TSHRPDE4B | |
| SCHEMBL598033 | 0.84 | MAPK1 (0.71) | MAPK1PRSS1TSHRPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015160842-A1 | METHODS AND FORMULATIIONS OF CAPSAICINOIDS AND CAPSINOIDS | FLEX PHARMA, INC. (US) | 2015-10-22 | — | — | WO | claimed |
| US-20190038573-A1 | ION CHANNEL ACTIVATORS AND METHODS OF USE | CLIFF-CARTWRIGHT CORPORATION | 2019-02-07 | — | — | US | disclosed |
| EP-3131541-A1 | ION CHANNEL ACTIVATORS AND METHODS OF USE | Flex Pharma, Inc. (US) | 2017-02-22 | — | — | EP | disclosed |
| US-20170042834-A1 | ION CHANNEL ACTIVATORS AND METHODS OF USE | CLIFF-CARTWRIGHT CORPORATION | 2017-02-16 | — | — | US | disclosed |
| WO-2015160843-A1 | ION CHANNEL ACTIVATORS AND METHODS OF USE | FLEX PHARMA, INC. (US) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015160842-A1 | METHODS AND FORMULATIIONS OF CAPSAICINOIDS AND CAPSINOIDS | FLEX PHARMA, INC. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-5221692-A | Antinociceptives | NATIONAL SCIENCE COUNCIL (TW) | 1993-06-22 | — | — | US | disclosed |