Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 15/20 | 0.51 |
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | CA12 | O43570 | 15/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550940 | 0.82 | CA9 (0.59) | CA9CA2CA12KMT2ATDP1 | |
| SCHEMBL22541408 | 0.76 | CA9 (0.53) | CA9CA2CA12KMT2ATDP1 | |
| SCHEMBL18026643 | 0.74 | CA12 (0.68) | CA9CA2CA12KMT2ATDP1 | |
| SCHEMBL7462238 | 0.73 | CA9 (0.49) | CA9CA2CA12KMT2ATDP1 | |
| SCHEMBL7307926 | 0.72 | CA12 (0.48) | CA9CA2CA12KMT2ATDP1 | |
| SCHEMBL11205876 | 0.70 | CA12 (0.46) | CA9CA2CA12KMT2ATDP1 | |
| SCHEMBL11192679 | 0.69 | CA12 (0.44) | CA9CA2CA12KMT2ATDP1 | |
| SCHEMBL30339085 | 0.69 | CA9 (1.00) | CA9CA2CA12ELANELMNA | |
| SCHEMBL107126 | 0.69 | CA9 (1.00) | CA9CA2CA12ELANELMNA | |
| SCHEMBL11195731 | 0.68 | CA12 (0.43) | CA9CA2CA12KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250696-A | Treatment of degenerative diseases | STERLING WINTHROP INC. (US) | 1993-10-05 | — | — | US | disclosed |