Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL12002873 | 0.97 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28379730 | 0.97 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL1598546 | 0.97 | TSHR (0.50) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28837031 | 0.95 | TSHR (0.47) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL2488390 | 0.95 | TSHR (0.47) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28144108 | 0.95 | TSHR (0.47) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28635161 | 0.95 | TSHR (0.47) | TSHRNAPRTTDP1 | |
| Pyridine SCHEMBL28077724 | 0.95 | TSHR (0.47) | TSHRNAPRTTDP1 | |
| SCHEMBL25867629 | 0.92 | — | — | |
| Pyridine SCHEMBL28885701 | 0.90 | TSHR (0.43) | TSHRNAPRTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361382-B1 | ANTIEPILEPTIC PYRAZOLOPYRIDINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-06-16 | — | — | EP | disclosed |
| US-4916140-A | CALCIUM CHANNEL BLOCKERS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-04-10 | — | — | US | disclosed |