Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | EZH2 | Q15910 | 7/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120920 | 0.83 | MEN1 (0.77) | MEN1KMT2AGLACYP2C9L3MBTL1 | |
| SCHEMBL169747 | 0.82 | EZH2 (0.80) | MEN1KMT2AGLACYP2C9L3MBTL1 | |
| SCHEMBL9501505 | 0.81 | MEN1 (0.48) | MEN1KMT2AGLACYP2C9L3MBTL1 | |
| SCHEMBL13575598 | 0.81 | MEN1 (0.71) | MEN1KMT2AGLACYP2C9L3MBTL1 | |
| SCHEMBL17067286 | 0.81 | MEN1 (0.71) | MEN1KMT2AGLACYP2C9L3MBTL1 | |
| SCHEMBL27636094 | 0.81 | EZH2 (0.70) | MEN1KMT2AGLACYP2C9L3MBTL1 | |
| SCHEMBL9501495 | 0.81 | MEN1 (0.65) | MEN1KMT2AGLACYP2C9L3MBTL1 | |
| SCHEMBL8738618 | 0.80 | EZH2 (0.74) | MEN1KMT2AEZH2 | |
| SCHEMBL310763 | 0.79 | KMT2A (0.82) | MEN1KMT2AGLACYP2C9L3MBTL1 | |
| SCHEMBL27821167 | 0.79 | KMT2A (0.72) | MEN1KMT2AGLACYP2C9L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241419-B1 | PIGMENTS CONTAINING PIPERIDYL GROUPS | SANDOZ AG (CH) | 1993-05-19 | — | — | EP | disclosed |
| US-4866113-A | COLORING POLYMERS | SANDOZ LTD. (CH) | 1989-09-12 | — | — | US | disclosed |
| US-4838943-A | Compounds useful as pigments containing one or more 2,2,6,6-tetraalkylpiperidine groups | SANDOZ LTD. (CH) | 1989-06-13 | — | — | US | disclosed |