Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439789 | 0.87 | APP (0.66) | MAOBRAB9AAPPKIF11NR4A2 | |
| SCHEMBL13439830 | 0.87 | SMPD1 (0.55) | MAOBRAB9AAPPSMPD1NR4A2 | |
| SCHEMBL23235861 | 0.86 | MAOB (0.56) | MAOBRAB9AAPPKIF11SMPD1 | |
| SCHEMBL9503621 | 0.84 | FFAR1 (0.52) | MAOBMAOA | |
| SCHEMBL23566110 | 0.81 | MAOB (0.54) | MAOBRAB9AKIF11SMPD1MAOA | |
| SCHEMBL9417707 | 0.81 | MAOB (0.50) | MAOBRAB9AAPPSMPD1MAOA | |
| SCHEMBL18664184 | 0.79 | MAOB (0.81) | MAOBRAB9AAPPSMPD1MAOA | |
| SCHEMBL29741480 | 0.79 | MAOB (0.81) | MAOBRAB9AAPPSMPD1MAOA | |
| SCHEMBL23540967 | 0.79 | MAOB (0.59) | MAOBRAB9AAPPKIF11SMPD1 | |
| SCHEMBL23541194 | 0.79 | MAOB (0.59) | MAOBRAB9AAPPSMPD1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288305-B1 | DI-T-BUTYLPHENYL ALKYL AND BENZYL ETHERS | RIKER LABORATORIES, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4973731-A | Di-t-butylphenyl alkyl and benzyl ether nitriles | RIKER LABORATORIES, INC. (US) | 1990-11-27 | — | — | US | disclosed |
| EP-0288305-A1 | Di-t-butylphenyl alkyl and benzyl ethers | RIKER LABORATORIES, INC. (US) | 1988-10-26 | — | — | EP | disclosed |