Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750540 | 0.84 | CA12 (0.46) | EPHX2NR1H4MAPTCYP1A2CYP2C9 | |
| SCHEMBL17845228 | 0.76 | EPHX2 (0.55) | EPHX2NR1H4MAPTCYP1A2CYP2C9 | |
| Butane SCHEMBL8721473 | 0.75 | NPC1 (0.59) | MAPTCA12CA1CA9LMNA | |
| Butane SCHEMBL6056712 | 0.75 | IDO1 (0.42) | LMNAGAA | |
| Butane SCHEMBL8002745 | 0.74 | IDO1 (0.42) | CYP2C19LMNAL3MBTL1 | |
| SCHEMBL5809008 | 0.74 | EPHX2 (0.51) | EPHX2NR1H4MAPTCYP1A2CYP2C9 | |
| Butane SCHEMBL3196642 | 0.73 | AGXT (0.44) | MAPTCYP1A2CA1CA2CA9 | |
| Butane SCHEMBL9443644 | 0.73 | APP (0.41) | MAPTCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL11077344 | 0.72 | CA12 (0.56) | EPHX2NR1H4MAPTCYP1A2CYP2C9 | |
| Butane SCHEMBL2636187 | 0.72 | PTPRZ1 (0.54) | CA1CA2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260939-B1 | MOLECULES WITH ANTIBODY COMBINING SITES THAT EXHIBIT CATALYTIC PROPERTIES | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5126258-A | Hydrolysis of polypeptides at predetermined site | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1992-06-30 | — | — | US | disclosed |
| US-5030717-A | Binding site which bind to reactant ligand, stabilization | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0260939-A2 | Molecules with antibody combining sites that exhibit catalytic properties | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1988-03-23 | — | — | EP | disclosed |