Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505466 | 0.84 | CYP19A1 (0.43) | CYP19A1KDM4EHRH3MEN1KMT2A | |
| SCHEMBL9504390 | 0.84 | HPGD (0.40) | KDM4EMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL9505291 | 0.84 | HPGD (0.40) | KDM4EMEN1KMT2AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL9503261 | 0.83 | CYP19A1 (0.42) | CYP19A1KDM4EHRH3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9503391 | 0.83 | CNR2 (0.39) | KDM4EMEN1KMT2AALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL9504486 | 0.83 | KDM4E (0.41) | KDM4EMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL9503493 | 0.83 | CNR2 (0.39) | KDM4EMEN1KMT2A | |
| SCHEMBL9503661 | 0.82 | MEN1 (0.42) | KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9504492 | 0.81 | MEN1 (0.41) | KDM4EMEN1KMT2A | |
| SCHEMBL9507122 | 0.81 | MEN1 (0.40) | KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336561-B1 | 2-PYRIDYLACETIC ACID DERIVATIVES, PREPARATIONS THEREOF, AND COMPOSITIONS CONTAINING THEM | SUNTORY LIMITED (JP) | 1993-07-28 | — | — | EP | claimed |
| EP-0336561-B1 | 2-PYRIDYLACETIC ACID DERIVATIVES, PREPARATIONS THEREOF, AND COMPOSITIONS CONTAINING THEM | SUNTORY LIMITED (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0336561-A1 | 2-Pyridylacetic acid derivatives, preparations thereof, and compositions containing them | SUNTORY LIMITED (JP) | 1989-10-11 | — | — | EP | disclosed |
| US-4843083-A | 2-pyridylacetic acid derivative, and pharmaceutical composition containing the same and method of treating a peptic ulcer | SUNTORY LIMITED (JP) | 1989-06-27 | — | — | US | disclosed |