Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19273 | 0.87 | — | — | |
| SCHEMBL31267242 | 0.87 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5167665 | 0.87 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Ethylene SCHEMBL5184263 | 0.84 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Formaldehyde SCHEMBL22631565 | 0.84 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Fluoride SCHEMBL2542918 | 0.84 | — | — | |
| Ethylene SCHEMBL461105 | 0.84 | TSHR (0.52) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| Charcoal, Activated SCHEMBL3744730 | 0.84 | — | — | |
| Water SCHEMBL1079113 | 0.84 | — | — | |
| SCHEMBL7154947 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370735-B1 | MANUFACTURE OF MODIFIED POLYPROPYLENE COMPOSITIONS USING NON-INTERMESHING TWIN SCREW EXTRUDER | Du Pont Canada Inc. (CA) | 1993-08-25 | — | — | EP | disclosed |
| EP-0370736-B1 | METHOD FOR MANUFACTURE OF MODIFIED POLYPROPYLENE COMPOSITIONS | Du Pont Canada Inc. (CA) | 1993-06-23 | — | — | EP | disclosed |
| US-5137975-A | Graft polymerization; melt grafting alpha,beta-unsaturated acid and anhydride in presence of organic peroxide as catalyst | DU PONT CANADA INC. (CA) | 1992-08-11 | — | — | US | disclosed |
| EP-0370736-A2 | Method for manufacture of modified polypropylene compositions | Du Pont Canada Inc. (CA) | 1990-05-30 | — | — | EP | disclosed |
| EP-0370735-A2 | Manufacture of modified polypropylene compositions using non-intermeshing twin screw extruder | Du Pont Canada Inc. (CA) | 1990-05-30 | — | — | EP | disclosed |