Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1972355 | 0.83 | FFAR1 (0.41) | CA2TAAR1ACACBCYP2A6SLC6A2 | |
| SCHEMBL1972357 | 0.83 | FFAR1 (0.41) | CA2TAAR1ACACBCYP2A6SLC6A2 | |
| SCHEMBL2266842 | 0.83 | FFAR1 (0.41) | CA2TAAR1ACACBCYP2A6SLC6A2 | |
| SCHEMBL242930 | 0.81 | GFER (0.42) | TAAR1ALDH1A1TSHRTDP1SLC6A4 | |
| SCHEMBL2269387 | 0.81 | GFER (0.42) | TAAR1ALDH1A1TSHRTDP1SLC6A4 | |
| SCHEMBL242929 | 0.81 | GFER (0.42) | TAAR1ALDH1A1TSHRTDP1SLC6A4 | |
| SCHEMBL9499665 | 0.80 | NQO1 (0.48) | ACACBTSHRTDP1 | |
| SCHEMBL9630894 | 0.80 | NQO1 (0.48) | ACACBTSHRTDP1 | |
| SCHEMBL9630902 | 0.80 | NQO1 (0.48) | ACACBTSHRTDP1 | |
| SCHEMBL2267252 | 0.79 | SLC6A4 (0.59) | TAAR1ACACBPPARGPPARASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538367-A1 | DERIVATIVES OF PITUITARY POSTERIOR LOBE HORMONES | Ferring AB (SE) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992000996-A1 | DERIVATIVES OF PITUITARY POSTERIOR LOBE HORMONES | FERRING AB (SE) | 1992-01-23 | — | — | WO | disclosed |