Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704272 | 1.00 | MAPK1 (0.46) | MAPK1TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL29378605 | 0.88 | MAPK1 (0.58) | MAPK1TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL544629 | 0.88 | MAPK1 (0.58) | MAPK1TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL28464772 | 0.84 | KMT2A (0.43) | MAPK1TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL29167176 | 0.82 | HPGD (0.47) | TDP1L3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL28099873 | 0.80 | MEN1 (0.53) | MAPK1TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL10449063 | 0.79 | SRC (0.42) | MAPK1TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL11300689 | 0.79 | SRC (0.42) | MAPK1TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL28099874 | 0.79 | KMT2A (0.50) | MAPK1TDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9711439 | 0.78 | MAPK1 (0.41) | MAPK1TDP1L3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244393-B1 | FLAME RETARDANT POLYPHENYLENE ETHER MOLDING COMPOSITIONS | FMC Corporation (US) | 1993-06-23 | — | — | EP | claimed |
| US-4710530-A | CONTAINING POLYBROMOTRIPHENYL PHOSPHATES | FMC CORPORATION (US) | 1987-12-01 | — | — | US | claimed |
| EP-0244393-A2 | Flame retardant polyphenylene ether molding compositions | FMC Corporation (US) | 1987-11-04 | — | — | EP | claimed |
| JP-1115955-A | — | — | None | — | — | JP | disclosed |
| EP-0244393-B1 | FLAME RETARDANT POLYPHENYLENE ETHER MOLDING COMPOSITIONS | FMC Corporation (US) | 1993-06-23 | — | — | EP | disclosed |
| JP-H01115955-A | FLAME-RETARDANT POLYPHENYLENE ETHER MOLDING COMPOSITION | FMC CORP | 1989-05-09 | — | — | JP | disclosed |
| US-4710530-A | CONTAINING POLYBROMOTRIPHENYL PHOSPHATES | FMC CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0244393-A2 | Flame retardant polyphenylene ether molding compositions | FMC Corporation (US) | 1987-11-04 | — | — | EP | disclosed |