Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11152533 | 0.86 | SPHK1 (0.43) | SPHK1SPHK2 | |
| Fluoride SCHEMBL9841688 | 0.83 | SPHK1 (0.42) | SPHK1SPHK2RARB | |
| SCHEMBL9632363 | 0.82 | SPHK1 (0.33) | SPHK1SPHK2RARBRARARARG | |
| SCHEMBL11162842 | 0.82 | SPHK1 (0.50) | SPHK1SPHK2 | |
| SCHEMBL9493351 | 0.81 | SPHK1 (0.39) | SPHK1SPHK2 | |
| SCHEMBL9841698 | 0.81 | SPHK1 (0.40) | SPHK1SPHK2RARB | |
| SCHEMBL17356663 | 0.80 | SPHK1 (0.39) | SPHK1SPHK2RARBRARARARG | |
| Fluoride SCHEMBL9841590 | 0.80 | SPHK1 (0.47) | SPHK1SPHK2 | |
| SCHEMBL11166462 | 0.79 | SPHK1 (0.36) | SPHK1SPHK2 | |
| Fluoride SCHEMBL9841514 | 0.79 | SPHK1 (0.49) | SPHK1SPHK2RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387032-B1 | TRIFLUOROBENZENE DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THE SAME | CHISSO CORP (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0387032-A1 | Trifluorobenzene derivatives and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1990-09-12 | — | — | EP | disclosed |