SCHEMBL9503903

SCHEMBL9503903

CC1(C)CC(NC(=O)C(C)(C)Br)CC(C)(C)N1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.50
GAA P10253 2/20 0.49
RECQL P46063 1/20 0.47
ALDH1A1 P00352 2/20 0.47
EZH2 Q15910 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
HSD17B10 Q99714 2/20 0.46
GLA P06280 2/20 0.46
ATM Q13315 1/20 0.46
HTT P42858 1/20 0.46
KDM4E B2RXH2 2/20 0.45
TP53 P04637 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL250845 0.81 GAA (0.51) POLBGAARECQLALDH1A1EZH2
SCHEMBL13297925 0.81 GAA (0.51) POLBGAARECQLALDH1A1EZH2
SCHEMBL11715934 0.79 POLB (0.49) POLBGAARECQLALDH1A1EZH2
SCHEMBL9504846 0.77 GAA (0.49) POLBGAARECQLALDH1A1EZH2
SCHEMBL3295977 0.77 RECQL (0.57) POLBGAARECQLALDH1A1EZH2
SCHEMBL10525290 0.77 RECQL (0.57) POLBGAARECQLALDH1A1EZH2
SCHEMBL27943592 0.76 GAA (0.43) POLBGAARECQLALDH1A1EZH2
SCHEMBL77511 0.75 RECQL (0.55) POLBGAARECQLALDH1A1EZH2
SCHEMBL28402532 0.75 POLB (0.57) POLBGAARECQLALDH1A1EZH2
SCHEMBL13547202 0.75 GAA (0.46) POLBGAARECQLALDH1A1EZH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4473694-A Process for the preparation of polysubstituted α-aminoacetamides THE B. F. GOODRICH COMPANY (US) 1984-09-25 US claimed
EP-0062322-A1 Improved process for synthesis of hindered amine stabilizers for polymeric materials The B.F. GOODRICH Company (US) 1982-10-13 EP claimed
EP-0172413-B1 PROCESS FOR PRODUCING PIPERIDINE DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-16 EP disclosed
US-5049604-A Heat, oxidation and light resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-17 US disclosed
EP-0172413-A2 Process for producing piperidine derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-02-26 EP disclosed
US-4500662-A STABILIZERS OF POLYMERIC MATERIALS AGAINST ULTRAVIOLET DEGRADATION THE B. F. GOODRICH COMPANY (US) 1985-02-19 US disclosed
US-4473694-A Process for the preparation of polysubstituted α-aminoacetamides THE B. F. GOODRICH COMPANY (US) 1984-09-25 US disclosed
EP-0062322-A1 Improved process for synthesis of hindered amine stabilizers for polymeric materials The B.F. GOODRICH Company (US) 1982-10-13 EP disclosed