Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402666 | 1.00 | TSHR (0.56) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL8813011 | 0.97 | MEN1 (0.60) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL6021572 | 0.97 | MEN1 (0.60) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL106781 | 0.97 | — | — | |
| SCHEMBL2551959 | 0.97 | TSHR (0.59) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL2960268 | 0.97 | TSHR (0.59) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL3062646 | 0.97 | TSHR (0.59) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL4390855 | 0.95 | MEN1 (0.62) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL7792032 | 0.95 | MEN1 (0.62) | TSHRMEN1KMT2ATHRBHTT | |
| SCHEMBL8956334 | 0.95 | MEN1 (0.62) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003412-A2 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |