Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.71 |
| ▸ | POLB | P06746 | 7/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.71 |
| ▸ | CCR6 | P51684 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.67 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | OGA | O60502 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395422 | 0.94 | MEN1 (0.66) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL14560563 | 0.86 | MEN1 (0.76) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL4100333 | 0.84 | MEN1 (0.73) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL29903439 | 0.83 | MEN1 (0.68) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL10261656 | 0.83 | MEN1 (0.68) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL14067864 | 0.83 | MEN1 (0.68) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL3860123 | 0.83 | HDAC1 (0.71) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL16213194 | 0.83 | MEN1 (1.00) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL12660214 | 0.82 | MEN1 (0.61) | MEN1KMT2APOLBNPSR1CCR6 | |
| SCHEMBL5114261 | 0.82 | HDAC3 (0.77) | MEN1KMT2APOLBNPSR1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281902-B1 | BIS-NAPHTHALIMIDES, THEIR PREPARATION AND USE | KNOLL AG (DE) | 1993-06-09 | — | — | EP | disclosed |
| US-4874863-A | Bisnaphthalimides | KNOLL AG (DE) | 1989-10-17 | — | — | US | disclosed |