Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.69 |
| ▸ | GAA | P10253 | 6/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | CASP1 | P29466 | 1/20 | 0.62 |
| ▸ | CASP7 | P55210 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24661296 | 0.87 | MAPT (0.58) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL21606300 | 0.83 | MAPT (0.54) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL9632299 | 0.82 | MAPT (0.57) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL30605798 | 0.82 | MAPT (1.00) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL864926 | 0.82 | MAPT (1.00) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL122553 | 0.81 | KDM4E (0.54) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL7569377 | 0.80 | GAA (0.76) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL4433442 | 0.80 | GAA (0.65) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL192100 | 0.80 | KDM4E (0.72) | MAPTGAAMAPK1KDM4EALDH1A1 | |
| SCHEMBL29375113 | 0.80 | KDM4E (0.72) | MAPTGAAMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543884-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ATHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |
| WO-1992003408-A1 | BENZANILIDE DERIVATIVES AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | RHONE-POULENC RORER LIMITED (GB) | 1992-03-05 | — | — | WO | disclosed |