Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275376 | 0.99 | POLB (0.66) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL16982216 | 0.94 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL13289974 | 0.94 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL13220831 | 0.94 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL14400544 | 0.93 | HTT (0.73) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL1494215 | 0.91 | POLB (0.56) | HTTPOLBAPEX1TDP1HDAC3 | |
| SCHEMBL708849 | 0.90 | POLB (0.64) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL5485944 | 0.90 | HTT (0.70) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL22490713 | 0.89 | HTT (0.68) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL22490709 | 0.89 | TSHR (0.69) | HTTPOLBAPEX1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5001117-A | — | — | None | — | — | JP | disclosed |
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-9507185-B2 | Switch element comprising a liquid crystalline medium | MERCK PATENT GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| US-20140293174-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-10-02 | — | — | US | disclosed |
| WO-2013060406-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-05-02 | — | — | WO | disclosed |
| US-7914485-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-7914485-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2011-03-29 | — | — | US | disclosed |
| US-20100016941-A1 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-20100016941-A1 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-7582078-B2 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| WO-2008045166-A2 | MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME | BOSTON SCIENTIFIC LIMITED (BB) | 2008-04-17 | — | — | WO | disclosed |
| US-20070191814-A1 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070191814-A1 | Medical device employing liquid crystal block copolymers and method of making the same | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2007-08-16 | — | — | US | disclosed |
| JP-H051117-A | SIDE CHAIN TYPE POLYMER LIQUID CRYSTAL | DAICEL CHEM IND LTD | 1993-01-08 | — | — | JP | disclosed |