SCHEMBL9504255

SCHEMBL9504255

CC#C[Si](CCCC)(CCCC)CCCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20658173 0.90 TSHR (0.40) TSHRLMNATHRB
SCHEMBL10731666 0.85 TSHR (0.38) TSHRLMNATHRB
SCHEMBL1953462 0.82
SCHEMBL20658198 0.80 TSHR (0.33) TSHRLMNATHRB
SCHEMBL9627014 0.77
SCHEMBL10725699 0.74 TSHR (0.33) TSHRLMNATHRB
SCHEMBL20658219 0.74 TSHR (0.47) TSHRLMNATHRB
SCHEMBL16828764 0.72
SCHEMBL9829591 0.72
SCHEMBL10536236 0.72 TSHR (0.38) TSHRLMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711075-B2 Method of preparing rubber composition including syndiotactic 1,2-polybutadiene KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-07-14 US disclosed
US-20190023815-A1 METHOD OF PREPARING RUBBER COMPOSITION INCLUDING SYNDIOTACTIC 1,2-POLYBUTADIENE KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2019-01-24 US disclosed
EP-0339516-B1 CATALYST AND PROCESS FOR THE PREPARATION OF POLYMERS OF TRI-SUBSTITUTED SILYLALKYNES AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-06-09 EP disclosed
US-4902763-A USING GROUP V OR VI METAL HALIDE CATALYST AND TRIALKYLGERMYALKYNE COMPOUND PROMOTER AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-02-20 US disclosed
EP-0343556-A2 Process for the polymerization of tri-substituted silylalkynes AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-11-29 EP disclosed
EP-0339516-A2 Catalyst and process for the preparation of polymers of tri-substituted silylalkynes AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-11-02 EP disclosed
US-4835229-A METAL HALIDE, TERTIARY AMINE AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-05-30 US disclosed