Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.97 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.97 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL2472356 | 0.98 | PTGS1 (0.93) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL253759 | 0.98 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL503709 | 0.97 | PTGS1 (0.97) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL9504307 | 0.97 | AKR1C3 (0.97) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL9504330 | 0.97 | AKR1C3 (0.97) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL9504293 | 0.97 | AKR1C3 (0.97) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| SCHEMBL31074330 | 0.95 | PTGS1 (0.93) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| 6-Methoxy-2-Naphthylacetic Acid SCHEMBL11306252 | 0.95 | PTGS1 (0.93) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| Methane SCHEMBL11413480 | 0.93 | PTGS1 (0.90) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 | |
| SCHEMBL10536961 | 0.84 | AKR1C3 (0.75) | AKR1C3AKR1C2PTGS1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548145-A1 | TOPICAL TREATMENT AND COMPOSITION | BEECHAM GROUP plc (GB) | 1993-06-30 | — | — | EP | claimed |
| WO-1992004019-A1 | TOPICAL TREATMENT AND COMPOSITION | BEECHAM GROUP PLC (GB) | 1992-03-19 | — | — | WO | claimed |
| EP-0548145-A1 | TOPICAL TREATMENT AND COMPOSITION | BEECHAM GROUP plc (GB) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004019-A1 | TOPICAL TREATMENT AND COMPOSITION | BEECHAM GROUP PLC (GB) | 1992-03-19 | — | — | WO | disclosed |