SCHEMBL9504354 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	PPARG	P37231	3/20	0.34

▸	THRA	P10827	3/20	0.34

▸	THRB	P10828	3/20	0.34

▸	S1PR5	Q9H228	7/20	0.34

▸	CNR2	P34972	3/20	0.34

▸	CNR1	P21554	2/20	0.33

▸	CCNE2	O96020	1/20	0.33

▸	CCNE1	P24864	1/20	0.33

▸	CDK2	P24941	1/20	0.33

▸	S1PR1	P21453	5/20	0.33

▸	S1PR3	Q99500	4/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9504314	0.99	CCNE2 (0.34)	PPARGTHRATHRBS1PR5CNR2
SCHEMBL9504362	0.92	MEN1 (0.39)	PPARGTHRATHRBS1PR5
SCHEMBL9504371	0.92	GAA (0.39)	PPARGCNR2CNR1
SCHEMBL9502550	0.92	MEN1 (0.39)	PPARGTHRATHRBS1PR5
SCHEMBL13841496	0.92	MEN1 (0.39)	PPARGTHRATHRBS1PR5
SCHEMBL9502765	0.92	MEN1 (0.39)	PPARGTHRATHRBS1PR5
SCHEMBL9504306	0.92	MEN1 (0.39)	PPARGTHRATHRBS1PR5
SCHEMBL9502574	0.92	MEN1 (0.39)	PPARGTHRATHRBS1PR5
SCHEMBL9504340	0.92	MEN1 (0.39)	PPARGTHRATHRBS1PR5
SCHEMBL9506514	0.92	MEN1 (0.39)	PPARGTHRATHRBS1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0364548-B1	OCTAFLUOROBIPHENYLS	MERCK PATENT GmbH (DE)	1993-06-09	—	—	EP	disclosed