Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30969123 | 0.86 | HSD17B10 (0.57) | KDM4EALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL151820 | 0.86 | HSD17B10 (0.57) | KDM4EALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL10714737 | 0.85 | KMT2A (0.55) | KDM4EALDH1A1TDP1TAAR1MEN1 | |
| SCHEMBL7151000 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL10823796 | 0.82 | CYP3A4 (0.55) | KDM4EALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL6904741 | 0.81 | AOC3 (0.50) | KDM4EALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL7123571 | 0.81 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL1461671 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL28124286 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL19692992 | 0.76 | KMT2A (0.54) | KDM4EALDH1A1SMN1; SMN2TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206460-B1 | L-PHENYLALANINE DEHYDROGENASE AND USE THEREOF | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1993-08-11 | — | — | EP | disclosed |
| EP-0513872-A1 | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-4849345-A | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0206460-A2 | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-30 | — | — | EP | disclosed |