Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.59 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.59 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504504 | 1.00 | PARP15 (0.59) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL9506626 | 0.92 | PARP15 (0.56) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL9506623 | 0.92 | PARP15 (0.56) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL9506613 | 0.90 | TP53 (0.58) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL9506610 | 0.90 | TP53 (0.58) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL416244 | 0.89 | PARP15 (0.72) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL9506651 | 0.89 | TP53 (0.61) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL9506603 | 0.89 | TP53 (0.61) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL9505871 | 0.89 | TP53 (0.61) | PARP15PARP10PARP2NR1H4TP53 | |
| SCHEMBL9506654 | 0.89 | TP53 (0.61) | PARP15PARP10PARP2NR1H4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372033-B1 | THERMOCHROMIC ESTERS | MERCK PATENT GmbH (DE) | 1993-08-11 | — | — | EP | claimed |