Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264239 | 0.84 | KCNH2 (0.31) | KCNH2 | |
| SCHEMBL217114 | 0.84 | KCNH2 (0.47) | KCNH2KDM5AKDM4CHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL22771631 | 0.81 | KCNH2 (0.45) | KCNH2KDM5AKDM4CHTR1DHTR1B | |
| SCHEMBL6700326 | 0.81 | — | — | |
| SCHEMBL5891723 | 0.79 | MEN1 (0.33) | KCNH2 | |
| Chloromethane SCHEMBL27830649 | 0.78 | KCNH2 (0.48) | KCNH2KDM5AKDM4CHTR1DHTR1B | |
| SCHEMBL516414 | 0.78 | KCNH2 (0.52) | KCNH2KDM5AKDM4CCA12CA1 | |
| SCHEMBL16137203 | 0.78 | KCNH2 (0.44) | KCNH2KDM5AKDM4CHTR1DHTR1B | |
| SCHEMBL218868 | 0.78 | KCNH2 (0.44) | KCNH2KDM5AKDM4CHTR1DHTR1B | |
| SCHEMBL12484771 | 0.78 | HTR1B (0.44) | KCNH2KDM5AKDM4CHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365982-B1 | ACRYLIC RUBBER COMPOSITION | TORAY SILICONE COMPANY, LIMITED (JP) | 1993-07-14 | — | — | EP | disclosed |
| US-5002995-A | Roll workability, rapid vulcanization rate | TORAY SILICONE COMPANY, LIMITED (JP) | 1991-03-26 | — | — | US | disclosed |
| EP-0365982-A1 | Acrylic rubber composition | TORAY SILICONE COMPANY, LIMITED (JP) | 1990-05-02 | — | — | EP | disclosed |