Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 16/20 | 0.72 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10509240 | 0.87 | PNP (0.73) | PNPHSP90AA1HSP90AB1XDH | |
| SCHEMBL27868175 | 0.86 | PNP (0.76) | PNPUSP2TSHREDNRAHTR2A | |
| SCHEMBL20970000 | 0.85 | PNP (0.74) | PNPHSP90AA1HSP90AB1XDH | |
| SCHEMBL9503573 | 0.84 | PNP (1.00) | PNPHPRT1 | |
| SCHEMBL9504543 | 0.84 | PNP (1.00) | PNPHPRT1 | |
| SCHEMBL9234450 | 0.83 | PNP (0.74) | PNP | |
| SCHEMBL3304421 | 0.83 | PNP (0.74) | PNPUSP2TSHREDNRAHTR2A | |
| SCHEMBL21433942 | 0.83 | PNP (0.74) | PNPUSP2TSHREDNRAHTR2A | |
| SCHEMBL10506929 | 0.83 | PNP (0.78) | PNPHSP90AA1HSP90AB1XDH | |
| SCHEMBL9502878 | 0.83 | PNP (0.80) | PNPHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |