Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | LPL | P06858 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.46 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506071 | 0.86 | PPARG (0.49) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL9504769 | 0.85 | PPARG (0.48) | PPARAPPARGSPHK2SPHK1 | |
| SCHEMBL9508869 | 0.84 | PPARA (0.52) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL9508797 | 0.83 | PPARG (0.50) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL9507490 | 0.83 | PPARG (0.50) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL9506855 | 0.83 | PPARG (0.50) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL9507514 | 0.83 | PPARG (0.50) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL9504753 | 0.83 | PPARG (0.50) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL9508836 | 0.83 | PPARG (0.50) | PPARAPPARGSPHK2SPHK1LPL | |
| SCHEMBL27671417 | 0.83 | PPARG (0.50) | PPARAPPARGSPHK2SPHK1LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |