Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542873 | 0.92 | KDM4E (0.50) | KDM4ESLC6A4MTNR1AMTNR1BCA4 | |
| Methylamine SCHEMBL10763289 | 0.87 | KDM4E (0.47) | KDM4ESLC6A4MTNR1AMTNR1BCA4 | |
| SCHEMBL9770385 | 0.85 | KDM4E (0.46) | KDM4ESLC6A4MTNR1AMTNR1BCA4 | |
| SCHEMBL9617076 | 0.83 | KDM4E (0.44) | KDM4ESLC6A4MTNR1AMTNR1BCA4 | |
| Bicarbonate SCHEMBL3270191 | 0.83 | GAA (0.52) | KDM4EMTNR1AMTNR1BPTGS1LMNA | |
| SCHEMBL12960634 | 0.83 | KMT2A (0.52) | KDM4ECA4LMNAGAAMEN1 | |
| SCHEMBL9296320 | 0.82 | KDM4E (0.47) | KDM4ESLC6A4MTNR1AMTNR1BCA4 | |
| SCHEMBL29159322 | 0.82 | KDM4E (0.47) | KDM4ESLC6A4MTNR1AMTNR1BCA4 | |
| SCHEMBL2356964 | 0.82 | CA4 (0.50) | KDM4ESLC6A4MTNR1AMTNR1BCA4 | |
| SCHEMBL10749798 | 0.81 | CA4 (0.64) | KDM4ECA4ALDH1A1LTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238765-B1 | 2,2-DIPHENOXY-N,N-DIMETHYLAMINOETHANE FOR IMPROVING CEREBRAL OXYGENATION | LIPHA - Lyonnaise Industrielle Pharmaceutique (FR) | 1993-07-21 | — | — | EP | claimed |
| EP-0238765-A2 | 2,2-Diphenoxy-N,N-dimethylaminoethane for improving cerebral oxygenation | LIPHA - Lyonnaise Industrielle Pharmaceutique (FR) | 1987-09-30 | — | — | EP | claimed |
| EP-0238765-B1 | 2,2-DIPHENOXY-N,N-DIMETHYLAMINOETHANE FOR IMPROVING CEREBRAL OXYGENATION | LIPHA - Lyonnaise Industrielle Pharmaceutique (FR) | 1993-07-21 | — | — | EP | disclosed |
| EP-0238765-B1 | 2,2-DIPHENOXY-N,N-DIMETHYLAMINOETHANE FOR IMPROVING CEREBRAL OXYGENATION | LIPHA - Lyonnaise Industrielle Pharmaceutique (FR) | 1993-07-21 | — | — | EP | disclosed |
| US-4762855-A | Novel pharmaceutical compositions improving oxygenation of the brain and a process for their production | ALBERT ROLLAND S.A. (FR) | 1988-08-09 | — | — | US | disclosed |
| EP-0238765-A2 | 2,2-Diphenoxy-N,N-dimethylaminoethane for improving cerebral oxygenation | LIPHA - Lyonnaise Industrielle Pharmaceutique (FR) | 1987-09-30 | — | — | EP | disclosed |
| EP-0238765-A2 | 2,2-Diphenoxy-N,N-dimethylaminoethane for improving cerebral oxygenation | LIPHA - Lyonnaise Industrielle Pharmaceutique (FR) | 1987-09-30 | — | — | EP | disclosed |
| EP-0238765-A2 | 2,2-Diphenoxy-N,N-dimethylaminoethane for improving cerebral oxygenation | LIPHA - Lyonnaise Industrielle Pharmaceutique (FR) | 1987-09-30 | — | — | EP | disclosed |