Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24589441 | 0.81 | KCNN4 (0.41) | KCNN4CA4SLC6A2SLC6A4RIPK1 | |
| SCHEMBL7171653 | 0.76 | ELANE (0.41) | TSHRPPARGALDH1A1MEN1RAB9A | |
| SCHEMBL11580065 | 0.75 | CA4 (0.43) | CA4SLC6A2SLC6A4RIPK1LTA4H | |
| SCHEMBL11373498 | 0.74 | PPARG (0.40) | TSHRLMNAPPARGALDH1A1ALOX15 | |
| SCHEMBL5278357 | 0.74 | CYP1A2 (0.36) | KCNN4CA4SLC6A2SLC6A4RIPK1 | |
| SCHEMBL4224012 | 0.74 | CA4 (0.48) | CA4RIPK1LTA4HTSHRMAPK1 | |
| SCHEMBL1660600 | 0.74 | CA4 (0.48) | CA4RIPK1LTA4HTSHRMAPK1 | |
| SCHEMBL10405698 | 0.74 | CA4 (0.48) | CA4SLC6A2SLC6A4RIPK1LTA4H | |
| SCHEMBL93074 | 0.74 | CA4 (0.48) | CA4SLC6A2SLC6A4RIPK1LTA4H | |
| SCHEMBL6047052 | 0.72 | CA4 (0.46) | CA4RIPK1LTA4HTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238765-B1 | 2,2-DIPHENOXY-N,N-DIMETHYLAMINOETHANE FOR IMPROVING CEREBRAL OXYGENATION | LIPHA - Lyonnaise Industrielle Pharmaceutique (FR) | 1993-07-21 | — | — | EP | claimed |
| EP-0216646-B1 | N,N-DIMETHYLETHYL AMINE OXIDE DERIVATIVE, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS OBTAINED | Albert ROLLAND S.A. Société dite (FR) | 1990-10-10 | — | — | EP | disclosed |
| US-4762855-A | Novel pharmaceutical compositions improving oxygenation of the brain and a process for their production | ALBERT ROLLAND S.A. (FR) | 1988-08-09 | — | — | US | disclosed |