Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967729 | 0.79 | HCRTR2 (0.46) | KMT2AMEN1GAANPC1HCRTR2 | |
| SCHEMBL8135631 | 0.77 | GSK3B (0.51) | KDM4EKMT2AMEN1GAAADORA2A | |
| SCHEMBL3743984 | 0.77 | NOTUM (0.52) | KDM4EMAPTGAAPKM | |
| SCHEMBL14564447 | 0.76 | MEN1 (0.55) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL6372051 | 0.75 | ADORA2A (0.60) | KDM4EALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL27905112 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL1931754 | 0.75 | GAA (0.65) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL1969272 | 0.75 | ADORA2A (0.64) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL24572924 | 0.75 | KMT2A (0.51) | KDM4EALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL2819846 | 0.74 | GSK3B (0.48) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375554-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-DIHYDROXYPHENYLSERINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0375554-A2 | Process for producing optically active threo-dihydroxyphenylserine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | disclosed |