Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17055675 | 0.86 | HSD17B10 (0.57) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6181841 | 0.84 | CTNNB1 (0.52) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL24572924 | 0.77 | KMT2A (0.51) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL21689281 | 0.76 | HDAC1 (0.68) | MAPTKDM4EALDH1A1HPGDTP53 | |
| SCHEMBL17055818 | 0.76 | NPC1 (0.71) | MAPTKMT2AMEN1TP53TDP1 | |
| SCHEMBL2822740 | 0.75 | HDAC1 (0.48) | MAPTALDH1A1HPGDTP53TDP1 | |
| SCHEMBL2221957 | 0.75 | HDAC1 (0.67) | MAPTKMT2AALDH1A1GAATSHR | |
| SCHEMBL21639144 | 0.75 | HDAC1 (0.68) | MAPTKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL17487352 | 0.75 | HDAC1 (0.67) | MAPTKDM4EALDH1A1L3MBTL1NPC1 | |
| SCHEMBL25002914 | 0.75 | HDAC1 (0.74) | MAPTKMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375554-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE THREO-DIHYDROXYPHENYLSERINE DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0375554-A2 | Process for producing optically active threo-dihydroxyphenylserine derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | disclosed |