Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GNRHR | P30968 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422525 | 0.87 | PSMB8 (0.56) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL17300875 | 0.82 | PSMB8 (0.51) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL8598047 | 0.79 | GAA (0.63) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL3968268 | 0.79 | MEN1 (0.63) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL21894108 | 0.79 | MEN1 (0.63) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL133292 | 0.79 | MAPT (0.50) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL30989189 | 0.79 | MEN1 (0.63) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL1663645 | 0.79 | MEN1 (0.97) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL3593276 | 0.77 | MEN1 (0.53) | MEN1KMT2AGAAMAPTPOLB | |
| SCHEMBL8598212 | 0.77 | KDM4E (0.62) | MEN1KMT2AGAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| US-4000295-A | ARACHNICIDAL | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |