SCHEMBL9505556

SCHEMBL9505556

C=CCCCCCCCCC[SiH](C)C

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.55
ALDH1A1 P00352 4/20 0.46
MAPT P10636 2/20 0.41
ABCC4 O15439 1/20 0.41
LMNA P02545 2/20 0.40
TRPA1 O75762 2/20 0.38
USP2 O75604 2/20 0.36
HPGD P15428 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LPAR3 Q9UBY5 2/20 0.35
LPAR2 Q9HBW0 1/20 0.35
CYP3A4 P08684 1/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28212344 1.00 TSHR (0.55) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL3292295 1.00 TSHR (0.55) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL3895006 1.00 TSHR (0.55) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL30468715 1.00 TSHR (0.55) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL29381470 1.00 TSHR (0.55) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL29381230 1.00 TSHR (0.55) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL29384750 1.00 TSHR (0.55) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL7624870 1.00 TSHR (0.55) TSHRALDH1A1MAPTABCC4LMNA
SCHEMBL3903560 0.97
SCHEMBL3909100 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0152011-B2 GAS-PERMEABLE LAMINATE TEIJIN LIMITED (JP) 1993-06-23 EP disclosed
US-4933082-A PERMSELECTIVE MEMBRANE ON A POROUS SUPPORT FOR SEPARATING GASES; HIGH STRENGTH TEIJIN LIMITED (JP) 1990-06-12 US disclosed
EP-0152011-B1 GAS-PERMEABLE LAMINATE TEIJIN LIMITED (JP) 1990-02-07 EP disclosed
EP-0152011-A2 Gas-permeable laminate TEIJIN LIMITED (JP) 1985-08-21 EP disclosed