Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28595008 | 0.81 | TDP1 (0.40) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL28361228 | 0.80 | SMN1; SMN2 (0.59) | TDP1L3MBTL1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7417080 | 0.76 | TDP1 (0.44) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL12980512 | 0.75 | TDP1 (0.47) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL11804026 | 0.75 | TDP1 (0.47) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL27935850 | 0.75 | TDP1 (0.43) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL28872509 | 0.73 | SMN1; SMN2 (0.65) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL11760572 | 0.72 | TDP1 (0.44) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL27991665 | 0.72 | TDP1 (0.41) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 | |
| SCHEMBL27997106 | 0.71 | TDP1 (0.47) | TDP1L3MBTL1SMN1; SMN2RAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0553284-A1 | SEMICARBAZONE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-04 | — | — | EP | disclosed |