Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24632378 | 0.84 | TSHR (0.43) | ALDH1A1TSHROPRM1METAP1GRIK1 | |
| SCHEMBL27487671 | 0.82 | TSHR (0.36) | ALDH1A1TSHROPRM1METAP1GRIK1 | |
| SCHEMBL3716398 | 0.79 | TSHR (0.43) | ALDH1A1TSHROPRM1TDP1GABBR2 | |
| SCHEMBL725898 | 0.79 | — | — | |
| SCHEMBL24900901 | 0.78 | TSHR (0.33) | ALDH1A1TSHROPRM1METAP1 | |
| SCHEMBL29226046 | 0.76 | METAP1 (0.33) | ALDH1A1TSHROPRM1METAP1 | |
| SCHEMBL2633042 | 0.76 | — | — | |
| SCHEMBL701649 | 0.76 | — | — | |
| SCHEMBL7215298 | 0.76 | — | — | |
| SCHEMBL249459 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376882-B1 | HETEROATOM CONTAINING PERFLUOROALKYL TERMINATED NEOPENTYL ACIDS AND SALTS THEREOF | CIBA-GEIGY AG (CH) | 1993-08-11 | — | — | EP | disclosed |
| US-5120364-A | Water and oil repellents | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0462063-A1 | Fluorinated paper sizes | CIBA-GEIGY AG (CH) | 1991-12-18 | — | — | EP | disclosed |
| EP-0376882-A1 | Heteroatom containing perfluoroalkyl terminated neopentyl acids and salts thereof | CIBA-GEIGY AG (CH) | 1990-07-04 | — | — | EP | disclosed |