SCHEMBL9505834

SCHEMBL9505834

CCc1c(F)c(F)c(-c2c(F)c(F)c(O)c(F)c2F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
DBH P09172 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10158116 0.92 ESR1 (0.36) ESR1DBH
SCHEMBL10336447 0.89 ESR1 (0.33) ESR1
SCHEMBL23848706 0.87 ESR1 (0.34) ESR1DBH
SCHEMBL13026660 0.87
SCHEMBL9505694 0.84
SCHEMBL20921888 0.81
SCHEMBL9502717 0.81 ESR1 (0.35) ESR1DBH
SCHEMBL17951892 0.79 ESR1 (0.31) ESR1
SCHEMBL5590219 0.79 ESR1 (0.31) ESR1
SCHEMBL9504320 0.78 ESR1 (0.41) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364548-B1 OCTAFLUOROBIPHENYLS MERCK PATENT GmbH (DE) 1993-06-09 EP disclosed