SCHEMBL950605

SCHEMBL950605

O=[C]C=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1672191 0.64
SCHEMBL10719628 0.64
SCHEMBL1411637 0.64
SCHEMBL11225409 0.64
SCHEMBL4725492 0.64
SCHEMBL9207872 0.56
SCHEMBL132811 0.56
SCHEMBL453625 0.56
SCHEMBL79832 0.56
SCHEMBL1499187 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011055135-A2 DANCE SHOE AND METHOD OF MANUFACTURE THEREOF A E STRUTHERS LIMITED (GB) 2011-05-12 WO claimed
WO-2007106797-A2 A METHOD OF USE FOR SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS JANSSEN PHARMACEUTICA, NV (BE) 2007-09-20 WO claimed
US-20070219245-A1 METHOD OF USE FOR SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS JANSSEN PHARMACEUTICA N.V. (BE) 2007-09-20 US claimed
EP-1802602-A1 SUBSTITUTED DIPIPERDINE CCR2 ANTAGONISTS JANSSEN PHARMACEUTICA N.V. (BE) 2007-07-04 EP claimed
WO-2006036527-A1 SUBSTITUTED DIPIPERDINE CCR2 ANTAGONISTS JANSSEN PHARMACEUTICA, N.V. (BE) 2006-04-06 WO claimed
US-20060069123-A1 Substituted dipiperidine CCR2 antagonists JANSSEN PHARMACEUTICA, N.V. (BE) 2006-03-30 US claimed
WO-2023163288-A1 MOBILE TERMINAL PROVIDED WITH DAMPING STRUCTURE 엘지전자 주식회사 2023-08-31 WO disclosed
US-20220274970-A1 INHIBITOR COMPOUNDS Cincera Therapeutics Pty Ltd (AU) 2022-09-01 US disclosed
CN-114450281-A Inhibitor compounds 辛塞拉治疗私人有限公司 2022-05-06 CN disclosed
US-10577308-B2 Sodium channel modulators The Florey Institute (AU) 2020-03-03 US disclosed
US-20180170891-A1 4H-Pyran Compounds as Insulin-Regulated Aminopeptidase (IRAP) Inhibitors MONASH UNIVERSITY (AU) 2018-06-21 US disclosed
US-20180072656-A1 Sodium Channel Modulators THE UNIVERSITY OF MELBOURNE (AU) 2018-03-15 US disclosed
US-9828351-B2 Enzyme interacting agents MONASH UNIVERSITY (AU) 2017-11-28 US disclosed
EP-0272868-A1 1,4-Benzodiazepines with 6-membered heterocyclic rings MERCK & CO. INC. (US) 1988-06-29 EP disclosed
EP-0248594-A2 Pharmacologically active 1,5-diaryl-3-substituted-pyrazoles and method for synthesizing the same ORTHO PHARMACEUTICAL CORPORATION (US) 1987-12-09 EP disclosed
EP-0229369-A2 Cephalosporins, process for their preparation and pharmaceutical compositions containing them Takeda Chemical Industries, Ltd. (JP) 1987-07-22 EP disclosed
EP-0225634-A2 Antibacterial compounds, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-06-16 EP disclosed
EP-0149884-A2 5-Pyridyl-1,3-thiazole derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1985-07-31 EP disclosed
EP-0048046-B1 METHOD FOR THE MANUFACTURE OF ETHYLIDENE DIACETATE SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1984-05-09 EP disclosed
US-3940441-A BACTERICIDE STERLING DRUG INC. (US) 1976-02-24 US disclosed